High Quality Geniposidic Acid CAS 24512-63-8 Geniposide Powder

  • CasNo24512-63-8
  • Molecular FormulaC17H24O10
  • Purity10%,30%,98%
  • AppearanceWhite Powder
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Quick Details

  • CasNo: 24512-63-8
  • Molecular Formula: C17H24O10
  • Appearance: White Powder
  • Delivery Time: 3
  • Throughput: 10000|Kilogram|Day
  • Purity: 10%,30%,98%

Product Name:Gardenoside Powder
Appearance:White crystalline Powder
Specification:99%
CAS No.:24512-63-8
Test Method:HPLC
Grade:Medicine Grade, Tech Grade, Medical Grade, Tech Grade
Shelf Life:2 Years
Brand:XAZB

Geniposide is an iridoid glycoside found in species of Gardenia that exhibits antioxidative, anti-diabetic, anti-inflammatory, neuroprotective, antiviral, and antithrombotic activities. Geniposide induces phase II enzymes and increases the expression of glutathione and glutathione peroxidase. Geniposide also inhibits phosphorylation of GSK-3β and stimulates expression of GLUT2, increasing insulin secretion in β cells. In LPS-stimulated epithelial cells, geniposide decreases production of toll-like receptor 4 (TLR4), IL-1β, IL-6, and TNF-α and downregulates activation of p38 MAPK, ERK, and NF-κB. In diabetic animal models of Alzheimer’s disease, geniposide decreases hippocampal levels of amyloid-β (Aβ). This compound also decreases enterovirus yields,
infectious activity, and ribosomal entry by inhibiting viral protein translation. In vitro, geniposide inhibits collagen-induced platelet aggregation and activity of phospholipase A2 (PLA2).

Function

1.Geniposide a variety of purposes, can be made of natural food coloring agent, is used to treat cardiovascular, liver and gallbladder diseases and diabetes raw materials such as drugs.


2.Gardenia has a clear role of cholecystokinin and its contraction was better than that of water, or even close to the effect of high-fat meal, so that the role of Gardenia with gallbladder stone row.


3.Gardenia extract SAP (severe pancreatitis) rats significantly decreased serum and tissue lipid peroxide activity level, and this maintenance of the body's own antioxidant, reducing oxygen free radicals and its cascading SAP reaction of the body caused by injury, reduce pancreatic injury will play beneficial effects.


4.Liver protection,Gardenia extract common bile duct ligation of GOT increased significantly reduce the effect, can increase the normal animals, Y, Z amount of proteins. UA contained in Gardenia can reduce serum transaminase, liver cancer cells was inhibited.


5.Hypotensive effect,The water extract of Gardenia extract or alcohol, whether oral, intraperitoneal or intravenous administration of antihypertensive effect of both, the rapid intravenous blood pressure, maintain a short time.


6.Prevention of atherosclerosis and thrombosis.
7.Sedation effect.
8.Anti-inflammatory effects and treatment of soft tissue injury
9.Anti-microbial effect.

Application

1.In healthy product industry,gardenia extract gardenoside is mainly used as product of dispelling heat, cooling blood and diuretic.


2.In pharmaceutical field ,gardenia extract gardenoside is mainly used as the raw material of drugs for treating cardiovascular and hepatobiliary diseases.