Product Details
Product Name:Tetracycline hydrochloride
CAS NO.: 64-75-5
Formula : C22H25ClN2O8
Appearance: Yellow crystalline powder
Specification:99%min
Tetracycline hydrochloride is a salt prepared from tetracycline taking advantage of the basic dimethylamino group which protonates and readily forms the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Tetracycline hydrochloride has broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-unit,s blocking protein synthesis.
Function
1.This product has a certain antibacterial effect on some anaerobes, but it is far inferior to metronidazole, clindamycin and chloramphenicol, so it is not used clinically. Over the years, due to the extensive application of tetracyclines, Gram-negative bacteria such as Staphylococcus and gram-negative bacilli, such as Staphylococcus, have been extensively drug-resistant to tetracycline.
Moreover, there are cross resistance among the species of the same kind. The action mechanism of this product is that the drug can specifically bind to the A location of the ribosomal 30S subunit, and prevent the binding of aminoyl tRNA on this site, thereby inhibiting the growth of peptide linkage and affecting the protein synthesis of bacteria.
2 .The first choice for the treatment of non bacterial infection of Chlamydia, Rickettsia, mycoplasma pneumonia disease, relapsing fever and other infections, but also for the treatment of brucellosis, cholera, tularemia, rat bite fever, anthrax, tetanus, plague, actinomycosis, gas gangrene and sensitive bacterial respiratory system, bile duct, urinary tract infection and skin and soft tissue infection etc..
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