99.9% pure Levamisole HCl Powder Levamisole Hydrochloride 16595-80-5

  • CasNo16595-80-5
  • Molecular FormulaC11H13ClN2S
  • Purity99.5%
  • AppearanceWhite Powder
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  • CasNo: 16595-80-5
  • Molecular Formula: C11H13ClN2S
  • Appearance: White Powder
  • Delivery Time: 3days after we receive the payment
  • Throughput: 1000|Kilogram|Month
  • Purity: 99.5%

99.9% pure Levamisole HCl Powder Levamisole Hydrochloride

 

What is Levamisole Hydrochloride

1.Levamisole Hydrochloride (Levamisole HCL), is an anthelmintic (anti-worm) agent  commonly used in large livestock such as cattle, pigs and sheep. In 1971 it was found to have immunostimulatory properties and investigation into its use in humans began to expand.

 

2.Currently, Levamisole HCL is used in humans for diseases related to imbalances in the regulation of immune responses or deficiencies of the immune system, including autoimmune diseases, chronic and recurrent diseases, chronic infections and cancer.

3.It has beneficial effects on host defense mechanisms and restores depressed immune responses in animals and humans.  Another interesting use of levamisole in humans is as a treatment for common warts (verruca vulgaris). 

4.News of its anthelmintic efficacy and immune system benefits has been known among aquatic hobbyists for years. The problem however, is that there is not much in the way of definitive information on its use and application in the hobby.

5.Anecdotal accounts of how it has worked for those 'outside the box' aquarists who first braved its use with fish, and accounts of personal experience with Levamisole in individual aquariums are helpful, but the 'your mileage may vary' factor is immense.

Appearance and properties: white to grey white crystalline powder
Melting point: about 59 (levamisole)
Absorbance: ≤0.2
Drying loss: ≤0.2
Ash content of sulfuric acid: ≤0.1%
Content: 98.5-101.0%
Specific rotation: ≥121.5°
Odor: no odor or almost no odor
6-Phenyl-2-dihydroimidazo[2,1-b]thiazole: ≤0.5%
Uses: The product is highly efficient broad-spectrum vermifuge, which is mainly used in ascariasis, ancylostomiasis and filariasis.
Packing: 33x50(cm) fiber drum, net weight 25kg.

 

How does Levamisole HCL work

How does Levamisole HCL work as an antiparasitic agent

Levamisole HCL is absorbed through the gut, can also be absorbed through the skin and is distributed throughout the body. 

 

Levamisole affects the neurotransmitters and paralyzes the worm (spastic paralysis). The fish then passes the inactive worms. Good gravel vacuuming is advised after treatment to remove the paralyzed (but still live) worms. 

It is not ovicidal, which means it will not affect eggs already present, but it will affect the larval stage of the worm. To ensure complete eradication of the parasite treat again after remaining eggs have hatched.

 

How does Levamisole HCL work as an immunomodulator

 

The mechanism of action for its immunostimulating effects are not well understood. It is believed that it restores cell-mediated immune function in peripheral T-lymphocytes and stimulates phagocytosis by monocytes. 

Levamisole hcl appears to restore depressed immune function rather than to stimulate 

response to above-normal levels. There are multitudes of medical studies being done with its use in humans and animals, the goal being to attain understanding of its immunomodulating mechanism. The mechanism will be defined, with time. 

However, at the time of the writing of this article, there is no complete answer to this question. For us, it is enough to know that it does stimulate immune function in fish that are suffering due to parasites or disease.