Factory Supply API Riluzole Powder CAS 1744-22-5 For Antiepileptic

  • CasNo1744-22-5
  • Molecular FormulaC28H54N8
  • Purity99% min
  • Appearance White powder

Product Details

Quick Details

  • CasNo: 1744-22-5
  • Molecular Formula: C28H54N8
  • Appearance: White powder
  • Delivery Time: 3
  • Throughput: 10000|Kilogram|Day
  • Purity: 99% min

Cas No:1744-22-5 
Use:amyotrophic lateral sclerosis 
Appearance:white powder

Riluzole is a drug used to treat amyotrophic lateral sclerosis. It delays the onset of ventilator-dependence or tracheostomy in selected patients and may increase survival by approximately 3–5 months.
Riluzole preferentially blocks TTX sensitive sodium channels, which are associated with damaged neurons. This reduces influx of calcium ions and indirectly prevents stimulation of glutamate receptors. Together with direct glutamate receptor blockade, the effect of the neurotransmitter glutamate on motor neurons is greatly reduced.
However, the action of riluzole on glutamate receptors has been controversial, as no binding of the molecule has been shown on any known receptor. In addition, as its antiglutamate action is still detectable in the presence of sodium channel blockers, it is also uncertain whether or not it acts via this way. Rather, its potent glutamate uptake activator activity seems to mediate many of its effects.


Treating patients with amyotrophic lateral sclerosis (ALS, Lou Gehrig disease) to prolong survival and/or to delay the need for surgery to help breathing (tracheostomy). It may also be used for other conditions as determined by your doctor.

Riluzole is a benzothiazole. Exactly how riluzole works is not known. It may prevent further damage to certain brain cells (motor neurons) responsible for controlling muscle function.


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